Peer-Reviewed Journal Details
Mandatory Fields
Dean KA, Aggarwal AK, Wharton RP;
2002
November
Trends In Genetics
Translational repressors in Drosophila.
Validated
()
Optional Fields
18
11
572
577

Translational regulation is an important aspect of gene regulation, particularly during early development of the fruit fly embryo when transcriptional mechanisms are untenable. Study of pattern formation and dosage compensation has identified several repressors that bind discrete sites in the untranslated portions of target mRNAs. These repressors do not work in isolation - each binds multiple sites in the appropriate mRNA, and the resulting RNA-protein complexes appear to recruit co-repressors by a variety of mechanisms.

http://www.ncbi.nlm.nih.gov/pubmed/12414187
Grant Details