Peer-Reviewed Journal Details
Mandatory Fields
McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG
2011
May
Pharmacology & Therapeutics
Altered peripheral toll-like receptor responses in the irritable bowel syndrome.
Validated
Optional Fields
33
9
1045
1052
Irritable bowel syndrome (IBS) is a stress-related disorder with disturbed brain-gut communication, gastrointestinal homeostasis and, based on recent evidence, low grade inflammation and an altered microbiota. The immune system is a critical regulator of the brain-gut axis. Toll-like receptors (TLRs) are pattern recognition molecules regulating innate immunity.
10.1111/j.1365-2036.2011.04624.x
Grant Details