GPs form an integral part of Irish primary care provision. However, current information concerning general practice structure, staffing and development in Ireland is quite limited. This report provides a profile of General Practice in Ireland in 2010 drawing on a national survey of practices using a standardised questionnaire. On average, there are 2.7 GPs per practice, although one in four practices remains single-handed. The majority of practices employ nursing 485(80.7%) and clerical 549(91.3%) support. A high proportion of practices have the following items of equipment: ECG machine 496(82.5%), 24 hour blood pressure monitor 481(80.1%), spirometer 383(63.8%), cryotherapy equipment 505(84%), minor surgery equipment 453(74.3%) and foetal monitor 484(80.5%). Using chi-square analysis, we find statistically significant positive relationships between nursing support and possession of each of the six items of medical equipment (X 2 = 81.57, p<0.01).