Peer-Reviewed Journal Details
Mandatory Fields
Shanahan, F.,O'Mahony, J.
2005
July
American Journal of Gastroenterology
The mycobacteria story in Crohn's disease
Validated
()
Optional Fields
100
7
1537
1538
The heterogeneity of Crohn's disease suggests that it would be unwise to dismiss an infectious contribution to the pathogenesis in a subset of patients. The most enduring infectious candidate has been Mycobacterium paratuberculosis, which appears to be widespread in nature and appears to have the potential to infect humans. However, there are many counterarguments to the notion that MAP causes Crohn's disease, and numerous observations are seemingly at variance with this concept.The heterogeneity of Crohn's disease suggests that it would be unwise to dismiss an infectious contribution to the pathogenesis in a subset of patients. The most enduring infectious candidate has been Mycobacterium paratuberculosis, which appears to be widespread in nature and appears to have the potential to infect humans. However, there are many counterarguments to the notion that MAP causes Crohn's disease, and numerous observations are seemingly at variance with this concept.
0002-92700002-9270
://WOS:000229911800019://WOS:000229911800019
Grant Details