Peer-Reviewed Journal Details
Mandatory Fields
Lynch NE, Stevenson NJ, Livingstone V, Murphy BP, Rennie JM, Boylan GB
2012
March
Epilepsia
The temporal evolution of electrographic seizure burden in neonatal hypoxic ischemic encephalopathy.
Validated
Optional Fields
53
3
549
557
Hypoxic ischemic encephalopathy (HIE) accounts for 60% of all neonatal seizures. There is emerging evidence that seizures cause additional injury to the developing brain that has sustained hypoxic ischemic injury. Temporal evolution of clinical seizure burden in HIE has been characterized, with maximum clinical seizure burden (the period of maximum seizure activity) being observed between 12 and 24 h of age. The purpose of our study was to investigate the distribution of electrographic seizure burden (the accumulated duration of seizures over a defined time period), following the initial hypoxic ischemic insult.
10.1111/j.1528-1167.2011.03401.x
Grant Details