Peer-Reviewed Journal Details
Mandatory Fields
Bottacini, F,Milani, C,Turroni, F,Sanchez, B,Foroni, E,Duranti, S,Serafini, F,Viappiani, A,Strati, F,Ferrarini, A,Delledonne, M,Henrissat, B,Coutinho, P,Fitzgerald, GF,Margolles, A,van Sinderen, D,Ventura, M
2012
September
Plos One
Bifidobacterium asteroides PRL2011 Genome Analysis Reveals Clues for Colonization of the Insect Gut
Validated
Optional Fields
HUMAN INTESTINAL-TRACT ESCHERICHIA-COLI LACTOCOCCUS-LACTIS SP-NOV TRANSCRIPTIONAL REGULATION DNA MICROARRAYS DIGESTIVE-TRACT GENE-EXPRESSION ACID TOLERANCE OXYGEN
7
Bifidobacteria are known as anaerobic/microaerophilic and fermentative microorganisms, which commonly inhabit the gastrointestinal tract of various animals and insects. Analysis of the 2,167,301 bp genome of Bifidobacterium asteroides PRL2011, a strain isolated from the hindgut of Apis mellifera var. ligustica, commonly known as the honey bee, revealed its predicted capability for respiratory metabolism. Conservation of the latter gene clusters in various B. asteroides strains enforces the notion that respiration is a common metabolic feature of this ancient bifidobacterial species, which has been lost in currently known mammal-derived Bifidobacterium species. In fact, phylogenomic based analyses suggested an ancient origin of B. asteroides and indicates it as an ancestor of the genus Bifidobacterium. Furthermore, the B. asteroides PRL2011 genome encodes various enzymes for coping with toxic products that arise as a result of oxygen-mediated respiration.
10.1371/journal.pone.0044229
Grant Details