O'Farrell, B,Benzie, JAH,McGinnity, P,de Eyto, E,Dillane, E,Coughlan, J,Cross, TF

2013

May

Plos One

Selection and Phylogenetics of Salmonid MHC Class I: Wild Brown Trout (Salmo trutta) Differ from a Non-Native Introduced Strain

Published

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MAJOR HISTOCOMPATIBILITY COMPLEX PEPTIDE-BINDING REGION RAINBOW-TROUT ONCORHYNCHUS-MYKISS ATLANTIC SALMON NATURAL-SELECTION BALANCING SELECTION TRANSSPECIES POLYMORPHISM CONVERGENT EVOLUTION PARASITE RESISTANCE

8

We tested how variation at a gene of adaptive importance, MHC class I (UBA), in a wild, endemic Salmo trutta population compared to that in both a previously studied non-native S. trutta population and a co-habiting Salmo salar population ( a sister species). High allelic diversity is observed and allelic divergence is much higher than that noted previously for cohabiting S. salar. Recombination was found to be important to population-level divergence. The alpha 1 and alpha 2 domains of UBA demonstrate ancient lineages but novel lineages are also identified at both domains in this work. We also find examples of recombination between UBA and the non-classical locus, ULA. Evidence for strong diversifying selection was found at a discrete suite of S. trutta UBA amino acid sites. The pattern was found to contrast with that found in re-analysed UBA data from an artificially stocked S. trutta population.

10.1371/journal.pone.0063035