Peer-Reviewed Journal Details
Mandatory Fields
Byrne, WL,DeLille, A,Kuo, C,de Jong, JS,van Dam, GM,Francis, KP,Tangney, M
2013
December
Journal of controlled release : official journal of the Controlled Release Society
Use of optical imaging to progress novel therapeutics to the clinic
Validated
Optional Fields
Gene therapy Cell therapy GREEN FLUORESCENT PROTEIN MESENCHYMAL STEM-CELLS SENTINEL LYMPH-NODE CANCER GENE-THERAPY IN-VIVO BREAST-CANCER REAL-TIME PHOTOACOUSTIC TOMOGRAPHY BIOLUMINESCENCE TOMOGRAPHY OVARIAN-CANCER
172
523
534
There is an undisputed need for employment and improvement of robust technology for real-time analyses of therapeutic delivery and responses in clinical translation of gene and cell therapies. Over the past decade, optical imaging has become the in vivo imaging modality of choice for many preclinical laboratories due to its efficiency, practicality and affordability, while more recently, the clinical potential for this technology is becoming apparent. This review provides an update on the current state of the art in in vivo optical imaging and discusses this rapidly improving technology in the context of it representing a translation enabler or indeed a future clinical imaging modality in its own right. (C) 2013 Elsevier B.V. All rights reserved.
10.1016/j.jconrel.2013.05.004
Grant Details