redox
ROS
ROS detection
ROS measurement
ROS signaling
hydrogen peroxide
nitric oxide
ROS probes
fluorescent probes
WALLED CARBON NANOTUBES
2-PHOTON FLUORESCENT-PROBE
CELLULAR OXIDATIVE STRESS
IMAGING NITRIC-OXIDE
HYDROGEN-PEROXIDE
LIVING CELLS
IN-VIVO
SELECTIVE DETECTION
METHIONINE OXIDATION
SUPEROXIDE FLASHES
Reactive oxygen species (ROS) play an essential role in facilitating signal transduction processes within the cell. However, the precise details of the redox dynamics involved are not well understood. The generation of ROS is tightly controlled both spatially and temporally within the cell, making the study of ROS dynamics particularly difficult. In order to measure these dynamics, precise tools that can specifically examine the relevant ROS are required. Recent advancements in methodologies for ROS measurement have allowed the study of ROS biology at a level of precision previously unachievable. Here, we discuss improvements to fluorescent ROS dye technologies, genetically encoded ROS reporters, nanoparticle delivery systems, and nanotube ROS probes. These technologies improve specificity, localization and sensitivity over previously available ROS probes.