Peer-Reviewed Journal Details
Mandatory Fields
Slattery, CN,O'Keeffe, S,Maguire, AR
2013
October
Tetrahedron-Asymmetry
Electronic effects of aryl-substituted bis(oxazoline) ligands on the outcome of asymmetric copper-catalysed C-H insertion and aromatic addition reactions
Validated
WOS: 6 ()
Optional Fields
ALPHA-DIAZOCARBONYL COMPOUNDS ENANTIOSELECTIVE SYNTHESIS COMPLEXES CYCLOPROPANATION DIAZOSULFONES DERIVATIVES MECHANISM
24
1265
1275
The effect of the modification of bis(oxazoline) ligands on the outcome of copper-catalysed C-H insertion and aromatic addition reactions is described. In general, these reactions display minimum sensitivity in terms of enantiocontrol to variation of the electronic properties of the aryl moiety of the ligand however, some influence is observed for C-H insertions employing naphthyl-substituted bis(oxazolines) and for aromatic addition reactions of biphenyl diazo ketone substrates. The synthesis of the modified bis(oxazolines), which include four novel structures, is also described. (C) 2013 Elsevier Ltd. All rights reserved.
10.1016/j.tetasy.2013.09.009
Grant Details