Conference Publication Details
Mandatory Fields
Riza, N. A.,Bokhari, A.
BIOS 2004 Biomedical Optics, San Jose, California
Agile optical confocal microscopy instrument architectures for high flexibility imaging. Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing
2004
January
Validated
0
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Optional Fields
77
8877
Ideally, a no-moving parts fast and agile scanning confocal microscope system is required that can produce true realtime 3-D scans with precision and repeatability. In this paper, such agile optical confocal microsopy designs are proposed that enable high speed precise non-invasive 3-D imaging. These compact confocal microscopes can provide real-time pin-point focussed imaging to enable confocal slices in-vivo, thus greatly reducing motion artifacts. These microscopes can be modified into interferometric microscopes for phase contrast imaging. The proposed microscopes can also greatly improve confocal fluorescence imaging as needed for cancer detection. An ultracompact confocal probe tip connected to a single ultra-thin fiber is another design option allowing flexibility for usage in tight cavities.Ideally, a no-moving parts fast and agile scanning confocal microscope system is required that can produce true realtime 3-D scans with precision and repeatability. In this paper, such agile optical confocal microsopy designs are proposed that enable high speed precise non-invasive 3-D imaging. These compact confocal microscopes can provide real-time pin-point focussed imaging to enable confocal slices in-vivo, thus greatly reducing motion artifacts. These microscopes can be modified into interferometric microscopes for phase contrast imaging. The proposed microscopes can also greatly improve confocal fluorescence imaging as needed for cancer detection. An ultracompact confocal probe tip connected to a single ultra-thin fiber is another design option allowing flexibility for usage in tight cavities.
://WOS:000223297800009://WOS:000223297800009
Grant Details