To the best of our knowledge, for the first time, biological Three Dimensional (3-D) imaging has been achieved using an electronically controlled optical lens to accomplish no-moving parts depth section scanning in a modified commercial 3D confocal microscope. Specifically, full 3-D views of a standard CDC blood vessel (enclosed in a glass slide) have been obtained using the modified confocal microscope operating at the red 633 nm laser wavelength.To the best of our knowledge, for the first time, biological Three Dimensional (3-D) imaging has been achieved using an electronically controlled optical lens to accomplish no-moving parts depth section scanning in a modified commercial 3D confocal microscope. Specifically, full 3-D views of a standard CDC blood vessel (enclosed in a glass slide) have been obtained using the modified confocal microscope operating at the red 633 nm laser wavelength.