Peer-Reviewed Journal Details
Mandatory Fields
Palmer LJ, Chapple IL, Wright HJ, Roberts A, Cooper PR
2012
August
Journal of periodontal research
Extracellular deoxyribonuclease production by periodontal bacteria.
Validated
()
Optional Fields
47
4
439
445
Whilst certain bacteria have long been known to secrete extracellular deoxyribonuclease (DNase), the purpose in microbial physiology was unclear. Recently, however, this enzyme has been demonstrated to confer enhanced virulence, enabling bacteria to evade the host's immune defence of extruded DNA/chromatin filaments, termed neutrophil extracellular traps (NETs). As NETs have recently been identified in infected periodontal tissue, the aim of this study was to screen periodontal bacteria for extracellular DNase activity.
10.1111/j.1600-0765.2011.01451.x
Grant Details