Other Publication Details
Mandatory Fields
Reviews
Endersen, L,O'Mahony, J,Hill, C,Ross, RP,McAuliffe, O,Coffey, A,Doyle, MP,Klaenhammer, TR
2014
January
Phage Therapy in the Food Industry
Validated
1
Optional Fields
bacteriophages foodborne pathogens spoilage biotherapeutics biosanitation biosensors ESCHERICHIA-COLI O157H7 CAMPYLOBACTER-JEJUNI COLONIZATION WALL-BINDING DOMAIN LISTERIA-MONOCYTOGENES BACTERIOPHAGE TREATMENT REDUCE SALMONELLA CLOSTRIDIUM-PERFRINGENS BROILER-CHICKENS MYCOBACTERIUM-PARATUBERCULOSIS VIRULENT BACTERIOPHAGE
Despite advances in modern technologies, the food industry is continuously challenged with the threat of microbial contamination. The overuse of antibiotics has further escalated this problem, resulting in the increasing emergence of antibiotic-resistant foodborne pathogens. Efforts to develop new methods for controlling microbial contamination in food and the food processing environment are extremely important. Accordingly, bacteriophages (phages) and their derivatives have emerged as novel, viable, and safe options for the prevention, treatment, and/or eradication of these contaminants in a range of foods and food processing environments. Whole phages, modified phages, and their derivatives are discussed in terms of current uses and future potential as antimicrobials in the traditional farm-to-fork context, encompassing areas such as primary production, postharvest processing, biosanitation, and biodetection. The review also presents some safety concerns to ensure safe and effective exploitation of bacteriophages in the future.
327
349
10.1146/annurev-food-030713-092415
Grant Details