Peer-Reviewed Journal Details
Mandatory Fields
Lindsay AJ, McCaffrey MW
2014
February
Biology of The Cell / Under The Auspices of The European Cell Biology Organization
Myosin Va is required for the transport of fragile X mental retardation protein (FMRP) granules.
Validated
Optional Fields
106
2
57
71
Fragile X mental retardation protein (FMRP) is a selective RNA binding protein that functions as a translational inhibitor. It also plays a role in directing the transport of a subset of mRNAs to their site of translation and several recent reports have implicated microtubule motor proteins in the transport of FMRP-messenger ribonucleoprotein (mRNP) granules in neurons. Earlier work reported the association of the actin-based motor protein myosin Va with FMRP granules.
10.1111/boc.201200076
Grant Details