Denihan NM, Looney A, Boylan GB, Walsh BH, Murray DM

2013

December

Clinical biochemistry

Normative levels of Interleukin 16 in umbilical cord blood.

Validated

WOS: 2 ()

46

18

1857

1859

The need for early and accurate prediction of outcome in hypoxic-ischaemic encephalopathy (HIE) remains critical. We have previously demonstrated that Interleukin 16 (IL-16) is raised in the umbilical cord blood (UCB) of infants with moderate and severe HIE and has the potential to be developed as a predictive biomarker. Normal reference ranges for IL-16 in UCB have not been previously described. The aim of this study was to determine normative levels of IL-16 in full term neonates using UCB following uncomplicated deliveries and to examine the effect of labour on cord IL-16 values.

10.1016/j.clinbiochem.2013.07.012