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K O’Donoghue
Outcomes in primparous women after investigation for two consecutive first trimester miscarriages
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Recurrent miscarriage, diagnosis, outcome, Cork University Maternity Hospital (CUMH)
Background: Recurrent miscarriage is defined as the loss of three or more consecutive miscarriages in the first trimester and affects 1-2% of women. Aim: To assess the diagnosis and outcome in women with two consecutive miscarriages who were investigated and treated at pregnancy loss clinic at Cork University Maternity Hospital. Method: Clinical details and outcomes of women attending the pregnancy loss clinic from January 2008 to July 2012 at CUMH were reviewed. We focussed on medical investigations performed and the subsequent pregnancy outcome. The data was divided into two groups; women less than and more than 35 years of age. Data was collected from the patient database and the electronic hospital patient management system. Results: 165 women with two consecutive miscarriages were seen and investigated in the Pregnancy Loss Clinic from January 2008 to July 2012. 59.3% of miscarriages were unexplained. In <35 years age group 77% women conceived again of which 55% had successful outcome whereas 21.8% of women had a third miscarriage. 23% of women in this age group did not avail our services. In >35 years group 69.5% women conceived again. Of these 27.5% women had subsequent miscarriage and 42% had successful pregnancy outcome. 30.4% of women in this group did not avail our services. Conclusion: Diagnosis is not achieved in a significant number of cases despite detailed investigations. Good pregnancy outcome can be achieved in the women with two recurrent miscarriages with appropriate management. - See more at: http://www.epostersonline.com/rcog2013/?q=node/1657#sthash.of8GmaOs.dpuf
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