Peer-Reviewed Journal Details
Mandatory Fields
Stevenson, N., Korotchikova, I., Temko, A., Lightbody, G., Marnane, W.P. and Boylan, G.,
Annals of Biomedical Engineering
An automated system for grading EEG abnormality in term neonates with hypoxic-ischaemic encephalopathy
WOS: 34 ()
Optional Fields
Electroencephalography, EEG, Newborn, Neonate, Background, Wigner-Ville distribution, Multi-class linear discriminant classifier, Hypoxic-ischaemic encephalopathy, Automated EEG grading system.
Automated analysis of the neonatal EEG has the potential to assist clinical decision making for neonates with hypoxic-ischaemic encephalopathy. This paper proposes a method of automatically grading the degree of abnormality in an hour long epoch of neonatal EEG. The automated grading system (AGS) was based on a multi-class linear classifier grading of short-term epochs of EEG which were converted into a long-term grading of EEG using a majority vote operation. The features used in the AGS were summary measurements of two sub-signals extracted from a quadratic time-frequency distribution: the amplitude modulation and instantaneous frequency. These sub-signals were based on a model of EEG as a multiplication of a coloured random process with a slowly varying pseudo-periodic waveform and may be related to macroscopic neurophysiological function. The 4 grade AGS had a classification accuracy of 83% compared to human annotation of the EEG (level of agreement, k = 0.76). Features estimated on the developed sub-signals proved more effective at grading the EEG than measures based solely on the EEG and the incorporation of additional sub-grades based on EEG states into the AGS also improved performance.
Grant Details
Science Foundation Ireland