Peer-Reviewed Journal Details
Mandatory Fields
Schellekens H, McNamara O, Dinan TG, McCarthy JV, McGlacken GP, Cryan JF
2013
April
The Journal of pharmacy and pharmacology
Semagacestat, a -secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor.
Validated
()
Optional Fields
65
4
528
538
Semagacestat, is a -secretase inhibitor, which belongs to a class of drugs that are being developed as therapeutic agents for Alzheimer's disease (AD). This study aims to evaluate another potential effect of semagacestat, namely its ability to stimulate the growth hormone secretagogue receptor (GHS-R1a), which may also contribute to its therapeutic efficacy.
10.1111/jphp.12010
Grant Details