Peer-Reviewed Journal Details
Mandatory Fields
Tramullas M, Finger BC, Moloney RD, Golubeva AV, Moloney G, Dinan TG, Cryan JF
2014
August
Biological psychiatry
Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice.
Validated
Optional Fields
76
4
340
348
Functional gastrointestinal disorders, which have visceral hypersensitivity as a core symptom, are frequently comorbid with stress-related psychiatric disorders. Increasing evidence points to a key role for toll-like receptor 4 (TLR4) in chronic pain states of somatic origin. However, the central contribution of TLR4 in visceral pain sensation remains elusive.
10.1016/j.biopsych.2013.11.004
Grant Details