Peer-Reviewed Journal Details
Mandatory Fields
Eileen M. O’Leary, David J. Jones, Fıona P. O’Donovan, Timothy P. O’Sullivan
2015
Unknown
Journal of Fluorine Chemistry
Synthesis of fluorinated oxygen- and sulfur-containing heteroaromatics
Published
()
Optional Fields
176
93
120
The incorporation of fluorine into a target molecule may have a considerable impact on its reactivity, selectivity, biological activity and physical properties. This is especially true in medicinal chemistry where fluorine is often employed as a bioisostere of hydrogen and where many important drug compounds also feature heteroaromatic rings. This work complements existing reviews on the synthesis of fluorinated, aromatic heterocycles, with a focus on less common oxygen-containing heteroaromatics as well as their sulfur-based analogues.
doi:10.1016/j.jfluchem.2015.06.002
Grant Details