Peer-Reviewed Journal Details
Mandatory Fields
Filan, P;Boylan, GB;Chorley, G;Davies, A;Fox, GF;Pressler, R;Rennie, JM
2005
April
An International Journal of Obstetrics and Gynaecology
The relationship between the onset of electrographic seizure activity after birth and the time of cerebral injury in utero
Validated
()
Optional Fields
NEONATAL SEIZURES SHEEP
112
504
507
In the fetal lamb model of hypoxic-ischaemic injury, the insult is followed by EEG depression, after which seizures emerge at 7-13 hours. We explored the relationship between the emergence of electrographic seizures and our estimate of the time of the cerebral injury in nine babies who underwent continuous video-EEG monitoring from soon after birth. Babies with prelabour insults had their first seizures before 12 hours of age, whereas those whose insult was peripartum had seizure onset at 18-20 hours of age. EEG seizure onset time could have important clinical and medico-legal applications, and be related to the time or severity of the insult, or both.
HOBOKEN
1470-0328
10.1111/j.1471-0528.2004.00476.x
Grant Details