Peer-Reviewed Journal Details
Mandatory Fields
Maguire, AR;O'Riordan, N
1999
December
Tetrahedron Letters
Dynamic kinetic resolution in the baker's yeast mediated reduction of 2-benzenesulfonylcycloalkanones
Validated
WOS: 13 ()
Optional Fields
BETA-KETO-ESTERS MICROBIAL REDUCTION STEREOCHEMICAL CONTROL DIASTEREOSELECTIVE REDUCTION ASYMMETRIC REDUCTION ORGANIC-SOLVENTS TRANSFORMATIONS DERIVATIVES
40
9285
9288
2-Benzenesulfonylcyclopentanone 1 and -cyclohexanone 2 undergo efficient dynamic kinetic resolution on treatment with baker's yeast, under a range of conditions including in organic solvents, to form the corresponding cis-2-benzenesulfonylcycloalkanols 5 and 6 in excellent enantiopurity. Reduction of larger ring derivatives is much less efficient. (C) 1999 Elsevier Science Ltd. All rights reserved.
OXFORD
0040-4039
Grant Details