Peer-Reviewed Journal Details
Mandatory Fields
Kharoshankaya L;Filan PM;Bogue CO;Murray DM;Boylan GB;
2014
July
Developmental Medicine and Child Neurology
Global suppression of electrocortical activity in unilateral perinatal thalamic stroke.
Validated
WOS: 3 ()
Optional Fields
56
7
We present an unusual case of persistent generalized electroencephalography (EEG) suppression and right-sided clonic seizures in a male infant born at 40(+2) weeks' gestation, birthweight 3240g, with an isolated unilateral thalamic stroke. The EEG at 13áhours after birth showed a generalized very low amplitude background pattern, which progressed to frequent electrographic seizures over the left hemisphere. The interictal background EEG pattern remained grossly abnormal over the next 48áhours, showing very low background amplitudes (<10ÁV). Magnetic resonance imaging revealed an isolated acute left-sided thalamic infarction. This is the first description of severe global EEG suppression caused by an isolated unilateral thalamic stroke and supports the role of the thalamus as the control centre for cortical electrical activity.
1469-8749
10.1111/dmcn.12365
Grant Details