Peer-Reviewed Journal Details
Mandatory Fields
Michael Reen and Timothy P. O'Sullivan
2016
June
Mini-Reviews in Organic Chemistry
The Application of Molecular Tethers in Controlling Axial Chirality
Published
()
Optional Fields
Atropisomeric biaryl compound, axial chirality, biaryls, stereoinduction, synthesis, tethers.
13
3
206
218
Atropisomeric biaryl compounds are an attractive target in organic chemistry due to their abundance in nature and their utility as ligands in catalysis. Among the methods available for their synthesis, the use of chiral tethers offers very high levels of stereocontrol. In this article, we review the application of molecular tethers in controlling axial chirality across a range of different ligands and natural products.
10.2174/1570193X13666160510114626
Grant Details