Conference Contribution Details
Mandatory Fields
Crean, A.M.
EuroSciCon Event: Vaccine Antigen Delivery
Design of Microneedles Formulations for Vaccine Delivery
Invited Lectures (Conference)
Optional Fields
Percutaneous delivery of vaccines to the skin via the use of microneedles involves the physical disruption the stratum corneum barrier. Vaccine scan be delivered using existing commercial approved formulations by applying the formulation to microneedle treated-skin or by injecting through hollow microneedles. However approaches that involve coating microneedles with vaccine, or the design of vaccine-loaded microneedles which dissolve following percutaneous application, require the design of solid vaccine formulations. The talk delivered will focus on the screening of formulation excipients and design of manufacturing processes to fabricate vaccine-loaded microneedle designs whilst maintaining vaccine integrity.