Peer-Reviewed Journal Details
Mandatory Fields
McKernan, DP; Fitzgerald, P; Dinan, TG; Cryan, JF;
Neurogastroenterology and Motility
The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat.
Optional Fields
Irritable bowel syndrome (IBS) is characterized by recurrent abdominal pain and altering bowel habit with a high percentage of patients displaying comorbid anxiety. Growing clinical and preclinical evidence suggests that probiotic agents may restore the altered brain-gut communication in IBS. In this study, we evaluated the efficacy of repeated treatment with three different probiotics in reducing visceral pain in visceral normosensitive (Sprague-Dawley [SD]) and visceral hypersensitive (Wistar-Kyoto [WKY]) rat strains.
Grant Details