Zhou, L.,Glennon, J. D.,Luong, J. H.,Reen, F. J.,O'Gara, F.,McSweeney, C.,McGlacken, G. P.

2011

October

Chemical communications (Cambridge, England)

Detection of the Pseudomonas Quinolone Signal (PQS) by cyclic voltammetry and amperometry using a boron doped diamond electrode

Validated

Altmetric: 1 ()

Boron/*chemistry Diamond/*chemistry Electrochemistry/*methods Electrodes Hydrogen-Ion Concentration Pseudomonas/*cytology Quinolones/*analysis/chemical synthesis/chemistry Quorum Sensing

47

37

10347

9

2-Heptyl-3-hydroxy-4-quinolone, known as the Pseudomonas Quinolone Signal, is a key regulator of bacterial cooperative behaviour known as quorum sensing. A simple electrochemical strategy was employed for its sensitive detection using a bare boron-doped diamond electrode by cyclic voltammetry and amperometry. PQS (and potentially other quinolones) was then detected in cultures of P. aeruginosa pqsL(-) mutant strains.

1364-548X (Electronic) 13

https://www.ncbi.nlm.nih.gov/pubmed/21853180

10.1039/c1cc13997e