Peer-Reviewed Journal Details
Mandatory Fields
Perez, JM;Cano, R;McGlacken, GP;Ramon, DJ
2016
January
RSC Advances
Palladium(II) oxide impregnated on magnetite as a catalyst for the synthesis of 4-arylcoumarins via a Heck-arylation/cyclization process
Validated
WOS: 10 ()
Optional Fields
H BOND FUNCTIONALIZATION ONE-POT SYNTHESIS DIARYLIODONIUM SALTS DIRECT ARYLATION ARYLBORONIC ACIDS MILD CONDITIONS REGIOSELECTIVE ARYLATION ORGANIC-SYNTHESIS IODONIUM SALTS COUMARINS
6
36932
36941
Heck-arylation/cyclization was achieved using heterogeneous palladium(II) oxide impregnated on magnetite catalyst (2.5 mol%) with a lower catalyst loading than that reported for similar processes. Ethanol was used as a non-toxic and bio-renewable solvent. Good yields were afforded using a broad range of substrates (40-98%). The catalyst could be partially recycled, and analyses confirmed the almost total reduction of palladium(II) oxide to palladium(0) as well as the iodine poissoning effect, which is the main barrier to complete recyclability.
CAMBRIDGE
2046-2069
10.1039/c6ra01731b
Grant Details