Peer-Reviewed Journal Details
Mandatory Fields
O'Brien, JF;Grace, PA;Perry, IJ;Hannigan, A;Moloney, MC;Burke, PE
2003
July
British Journal of Surgery
Randomized clinical trial and economic analysis of four-layer compression bandaging for venous ulcers
Validated
WOS: 48 ()
Optional Fields
LEG ULCERS
90
794
798
Background: The aim of this study was to compare the cost-effectiveness of four-layer compression bandaging for venous leg ulcers with that of other available treatments. Methods: In this pragmatic trial, 200 patients with a venous leg ulcer were randomized either to four-layer bandaging (intervention group; n = 100) or to continue their usual system of care (control group; n = 100). The follow-up for each patient was 12 weeks. Analysis was by intention to treat; the main outcome measures were time to healing and cost to the health board per leg healed. Results: Baseline characteristics were well matched in the two groups. The Kaplan-Meier estimate of the healing rate at 3 months was 54 per cent with four-layer bandaging and 34 per cent in the control group. Throughout the 3 months, four-layer bandaging healed leg ulcers significantly earlier (P = 0.006). There was a significant reduction in the median cost per leg healed with four-layer bandaging (E210 versus; E234; P = 0.040). Conclusion: Four-layer bandaging is currently the most effective method of treating venous leg ulcers in a community setting.
CHICHESTER
0007-1323
10.1002/bjs.4167
Grant Details