Peer-Reviewed Journal Details
Mandatory Fields
Korotchikova, I;Stevenson, NJ;Livingstone, V;Ryan, CA;Boylan, GB
2016
April
Clinical Neurophysiology
Sleep-wake cycle of the healthy term newborn infant in the immediate postnatal period
Validated
WOS: 26 ()
Optional Fields
HYPOXIC-ISCHEMIC ENCEPHALOPATHY AMPLITUDE-INTEGRATED EEG FULL-TERM PROGNOSTIC VALUE STRESS-RESPONSE NEONATAL EEG PREMATURE-INFANTS CESAREAN-SECTION QUIET SLEEP DELIVERY
127
2095
2101
Objective: To examine sleep-wake cycle (SWC) composition of healthy term infants in the immediate postnatal period using EEG, and investigate factors that might influence it. Methods: Multichannel video-EEG was recorded for a median of 61.9 min (IQR: 60.0-69.3). The absolute and relative scores of sleep states were calculated for each infant's recording. Parametric/non-parametric statistical tests and multiple linear regression analysis were used to investigate the influence of perinatal factors on SWC composition. Results: Eighty healthy term infants aged 1-36 h were studied. A well-developed SWC was evident as early as within the first 6 h after birth. The mean (SD) percentage of active sleep (AS) was 52.1% (12.9) and quiet sleep (QS) was 38.6% (12.5). AS was longer and QS shorter in infants delivered by elective caesarean section (CS) compared to infants delivered by vaginal delivery or emergency CS. Conclusions: This is the first large cohort EEG study that has quantified neonatal sleep. SWC is clearly present immediately after birth, it is dominated by AS, and is influenced by mode of delivery. Significance: This knowledge of the early neonatal EEG/SWC can be used as reference data for EEG studies of neurologically compromised infants. (C) 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
CLARE
1388-2457
10.1016/j.clinph.2015.12.015
Grant Details