Peer-Reviewed Journal Details
Mandatory Fields
Hennessy, AA;Ross, RP;Fitzgerald, GF;Caplice, N;Stanton, C
2014
August
Current Cardiology Reports
Role of the Gut in Modulating Lipoprotein Metabolism
Validated
WOS: 12 ()
Optional Fields
CONJUGATED LINOLEIC-ACID INTESTINAL EPITHELIAL-CELLS TRIGLYCERIDE TRANSFER PROTEIN SALT-STIMULATED LIPASE POSTPRANDIAL LIPID-METABOLISM CARBOXYL ESTER LIPASE APOLIPOPROTEIN A-IV CHAIN FATTY-ACIDS PANCREATIC LIPASE BINDING PROTEIN
16
The intestinal production of lipoproteins is one of the key processes by which the body prepares dietary lipid for dissemination to locations throughout the body where they are required. Paramount to this is the relationship between dietary lipid and the enterocytes that line the gut, along with the processes which prepare this lipid for efficient uptake by these cells. These include those which occur in the mouth and stomach along with those which occur within the intestinal lumen itself. Additionally, the interplay between digested lipid, dual avenues for lipid uptake by enterocytes (passive and lipid transporter proteins), a system of intercellular lipid resynthesis and transport, and a complex system of lipoprotein synthesis yield a system open to significant modulation. In this review, we will attempt to outline the processes of lipid digestion, lipoprotein synthesis and the exogenous and endogenous factors which exert their influence.
NEW YORK
1523-3782
10.1007/s11886-014-0515-2
Grant Details