Peer-Reviewed Journal Details
Mandatory Fields
Hegarty, JW;Guinane, CM;Ross, RP;Hill, C;Cotter, PD
2017
December
Probiotics And Antimicrobial Proteins
Lack of Heterogeneity in Bacteriocin Production Across a Selection of Commercial Probiotic Products
Validated
WOS: 5 ()
Optional Fields
LACTIC-ACID BACTERIA STREPTOCOCCUS-SALIVARIUS K12 LACTOBACILLUS-ACIDOPHILUS ANTIMICROBIAL PEPTIDES GASTROINTESTINAL-TRACT GENOMIC DIVERSITY LACTACIN-B STRAIN FOOD
9
459
465
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit to the host. Bacteriocin production has often been mooted as a desirable probiotic trait and, in specific cases, has been shown to promote probiotic survival within the gastrointestinal tract, contribute to the control of pathogens and even influence host gene expression in the gut. However, it is not clear what proportion of probiotic strains routinely found in commercial products produces bacteriocins, and additionally, it is not known which bacteriocins are produced most frequently. To address this, we conducted a culture-based assessment of the bacteriocinogenic ability of bacterial strains found in a variety of commercially available probiotic products. We detected eight bacteriocinproducing isolates from 16 tested products. Interestingly, in all cases, the isolates were Lactobacillus acidophilus, and the bacteriocin produced was identified as the narrow spectrum class II bacteriocin, lactacin B. The apparent absence of other bacteriocin-producing strains from across these products suggests a lack of heterogeneity in bacteriocin production within probiotic products and suggests that bacteriocin production is not being optimally harnessed as a probiotic trait.
NEW YORK
1867-1306
10.1007/s12602-017-9326-2
Grant Details