Peer-Reviewed Journal Details
Mandatory Fields
Mahon, P,Greene, BR,Lynch, EM,McNamara, B,Shorten, GD;
2008
August
Anaesthesia
Can state or response entropy be used as a measure of sleep depth?
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Optional Fields
BISPECTRAL INDEX HYPOXEMIA SURGERY
63
1309
1313
In this prospective observational study we examined the potential of the spectral entropy measures 'state' and 'response' entropy (Entropy (TM) monitor), as measures of sleep depth in 12 healthy adult subjects. Both median state and response entropy values varied significantly with sleep stage (p = 0.017 and p = 0.014 respectively; ANOVA). Median state or response entropy did not decrease significantly during the transition from awake to stage I sleep (p > 0.017). State entropy values decreased significantly between sleep stages I and II (p < 0.001). Both state and response entropy values were significantly less (40 and 45 arbitrary units respectively) in stage III (slow wave sleep) vs stage II sleep (p = 0.008). We conclude that state and response entropy values, when expressed as a function of time, may be a useful means of quantifying aspects of sleep.
DOI 10.1111/j.1365-2044.2008.05675.x
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