Peer-Reviewed Journal Details
Mandatory Fields
Keohane, J,Quigley, EMM;
2006
May
World Journal of Gastroenterology
Functional dyspepsia: The role of visceral hypersensitivity in its pathogenesis
Validated
()
Optional Fields
visceral hypersensitivity motor dysfunction Helicobacter pylori psychosocial HELICOBACTER-PYLORI INFECTION IRRITABLE-BOWEL-SYNDROME CHRONIC IDIOPATHIC DYSPEPSIA BRAIN-GUT AXIS GASTRIC DISTENSION NONULCER DYSPEPSIA PROXIMAL STOMACH WALL TENSION PERCEPTION SENSITIVITY
12
2672
2676
Functional, or non-ulcer, dyspepsia (FD) is one of the most common reasons for referral to gastroenterologists. It is associated with significant morbidity and impaired quality of life. Many authorities believe that functional dyspepsia and irritable bowel syndrome represent part of the spectrum of the same disease process. The pathophysiology of FD remains unclear but several theories have been proposed including visceral hypersensitivity, gastric motor dysfunction, Helicobacter pylori infection and psychosocial factors. In this review, we look at the evidence, to date, for the role of visceral hypersensitivity in the aetiology of FD. (C) 2006 The WJG Press. All rights reserved.
Grant Details