Peer-Reviewed Journal Details
Mandatory Fields
Mulcahy, H., O'Callaghan, J., O'Grady, E.P., Adams, C., and O'Gara, F.;
2006
January
Infection and Immunity
The post-transcriptional regulator RsmA plays a role in the interaction between Pseudomonas aeruginosa and human airway epithelial cells by positively regulating the type III secretion system.
Published
()
Optional Fields
ACTIN CYTOSKELETON DISRUPTION EXOENZYME-S REGULON VIRULENCE EXPRESSION INVASION GENES PAO1 PROTEIN EFFLUX INTERNALIZATION
74
3012
3015
Posttranscriptional regulation of certain virulence-related genes in Pseudomonas aeruginosa is brought about by RsmA, a small RNA-binding protein. During interaction with airway epithelial cells, RsmA promoted actin depolymerization, cytotoxicity, and anti-internalization of P. aeruginosa by positively regulating the virulence-associated type III secretion system.
DOI 10.1128/IAI.74.5.3012-3015.2006
Grant Details