Mandatory Fields

Authors

Margolles, A,Moreno, JA,van Sinderen, D,Reyes-Gavilan, CGD;

Year

2005

Month

May

Journal

Antimicrobial Agents and Chemotherapy

Title

Macrolide resistance mediated by a Bifidobacterium breve membrane protein

Status

Validated

Times Cited

()

Optional Fields

Keywords

ANTIMICROBIAL SUSCEPTIBILITY LACTOCOCCUS-LACTIS ANTIBIOTIC SUSCEPTIBILITY EXPRESSION NISIN ACIDS

Volume

Issue

Start Page

4379

End Page

4381

Abstract

A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis. Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides.

Publisher Location

ISBN / ISSN

Edition

URL

DOI Link

DOI 10.1128/AAC.49.10.4379-4381.2005

Grant Details

Funding Body

Grant Details