JENNINGS, WB,KOCHANEWYCZ, MJ,LOVELY, CJ,BOYD, DR;

1994

November

Rna-A Publication of The Rna Society

OPTICALLY-ACTIVE N-PHOSPHINOYLOXAZIRIDINES - PREPARATION AND CHIRAL OXYGEN-TRANSFER TO PROCHIRAL SULFIDES

Validated

()

ASYMMETRIC OXIDATION SULFOXIDES

2569

2570

Optically active N-phosphinoyloxaziridines 3a and 3b containing a chiral phosphorus centre have been prepared; these compounds oxidise aryl alkyl sulfides to chiral sulfoxides with 34-70% enantiomeric excess.