KEANE, D,JENKINS, DM,HIGGINS, T,ONEILL, M,MULCAHY, MF,FERRISS, JB;

1995

November

European Journal of Obstetrics & Gynecology and Reproductive Biology

THE EFFECT OF INTERMITTENT STEROID-THERAPY ON ANTISPERM ANTIBODY-LEVELS

Validated

()

ANTISPERM ANTIBODY STEROID THERAPY PREGNANCY ANTISPERM ANTIBODIES

63

75

79

Sperm-bound antisperm antibody levels were measured in 10 males in subfertile partnerships who were treated with high dose intermittent prednisolone therapy over a period up to 9 months. Antibody levels fell in all patients during therapy, although a transient rise occurred after 2-4 months. There were low treatment complication rates. Four pregnancies occurred during the treatment of the 10 patients. There was no correlation between pregnancy and change in antibody.