T. A. J. Siddiqui, B. G. Ghule, S. Shaikh, P. V. Shinde, K. C. Gunturu, P. K. Zubaidha, J. M. Yun, C. O'Dwyer, R. S. Mane, K. H. Kim

2018

May

RSC Advances

Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives

Published

()

8

17373

17379

We report the preparation of graphene oxide nanoparticles (GONPs), a metal-free, heterogeneous, nontoxic, reusable and mesoporous green-(acid)-catalyst obtained by sugar carbonization through a microwave chemical synthesis method for the synthesis of bio-active benzylpyrazolyl coumarin derivatives (BCDs) under thermal conditions (50
C) in ethanol solvent. The obtained products were purified by recrystallization from ethanol, assuring usability of GONPs in multicomponent reactions (MCRs) that could find wide application in the synthesis of a variety of biologically potent molecules of therapeutic significance.

http://pubs.rsc.org/en/Content/ArticleLanding/2018/RA/C7RA12550J

10.1039/C7RA12550J