David J. Jones, Uday B. Rao Khandavilli, Eileen M. O’Leary, Simon E. Lawrence, Timothy P. O’Sullivan

2018

Unknown

SynOpen

Efficient S-Acylation of Thiourea

Published

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isothiourea,thiourea, organosulfur, sulfur transfer

2

4

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Efficient S-acylation of thiourea using a variety of acid chlorides is reported. Structurally diverse aryl and alkyl substrates are compatible with this methodology. Confirmation that acylation occurs exclusively­ on the sulfur atom of thiourea is provided by single-crystal X-ray crystallographic analysis.

10.1055/s-0037-1610370

UCC Strategic Research Fund