Flynn, CJ; Elcoate, CJ; Lawrence, SE; Maguire, AR;

2010

February

Journal of the American Chemical Society

Highly enantioselective intramolecular copper catalyzed C-H insertion reactions of alpha-diazosulfones.

Validated

()

132

4

1184

1185

Excellent enantiocontrol (up to 98% ee) is achieved in copper catalyzed C-H insertions of alpha-diazosulfones to form thiopyrans, with up to 60% ee in C-H insertions leading to sulfolanes.

10.1021/ja909713a