Lindner, Juliano De Dea and Canchaya, Carlos and Zhang, Ziding and Neviani, Erasmo and Fitzgerald, Gerald F. and van Sinderen, Douwe and Ventura, Marco;

2007

November

International Journal of Food Microbiology

Exploiting Bifidobacterium genomes: The molecular basis of stress response

Validated

Scopus: 40 ()

120

1-2

13

24

Bifidobacteria represent important human commensals because of their perceived contribution to the maintenance of a balanced gastro intestinal tract (GIT). In recent years bifidobacteria have drawn much scientific attention because of their use as live bacteria in numerous food preparations with various health-related claims. For such reasons these bacteria constitute a growing area of interest with respect to genomics, molecular biology and genetics. This review will discuss the current knowledge on the molecular players that allow bifidobacteria to contend with heat-, osmotic-, bile-and acidic stress. Here, we describe the principal molecular chaperones involved in such stresses, as well as their use as phylogenetic markers for gaining insight into the evolutionary history of high G+C Gram positive bacteria. 2007 Elsevier B.V. All rights reserved.

10.1016/j.ijfoodmicro.2007.06.016