Peer-Reviewed Journal Details
Mandatory Fields
Cashman KD;
2007
January
Novartis Foundation symposium
Calcium and vitamin D.
Validated
()
Optional Fields
282
123
11
Calcium is required for normal growth and development as well as maintenance of the skeleton. Vitamin D is also essential for intestinal calcium absorption and plays a central role in maintaining calcium homeostasis and skeletal integrity. In addition, both micronutrients have important roles in non-skeletal-related physiological processes. Of concern, significant proportions of some population groups fail to achieve the recommended calcium intakes in a number of western countries. Furthermore, while cutaneous biosynthesis upon exposure of skin to ultraviolet B light is the major source of vitamin D for most people, this does not occur during winter time. Thus, there is an increased reliance on dietary sources during winter months to help maintain adequate vitamin D status. Since vitamin D is found naturally only in a limited number of foods, the usual dietary vitamin D intake by many European populations is not sufficient to maintain adequate vitamin D status. This paper will briefly review these important issues together with consideration of the potential role for supplementation with calcium and vitamin D in terms of improving their intakes in the population. It will also focus on the issues of efficacy as well as safety considerations of supplements.
Grant Details