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Tedesco, S, Doyle, H, Redmond, G, Sheehan, D;
2008
July
Gold Nanoparticles and Oxidative Stress In Mytilus Edulis
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Little is known about potential environmental impact of nanoparticles. Gold namoparticles can cause unexpected biological responses. Here, Mytilus edulis were exposed (24 h) to gold-citrate nanoparticles (GNP), menadione and both compounds simultaneously (GNP/menadione). Protein ubiquitination and carbonylation were determined in gill, mantle and digestive gland, along with traditional oxidative stress biomarkers; catalase activity and neutral red retention time assay (haemolymph). 2DE gels were performed on gill proteins (menadione; GNP/menadione). Our results reveal that GNP may induce oxidative stress. (C) 2008 Elsevier Ltd. All rights reserved..
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DOI 10.1016/j.marenvres.2008.02.044
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