Peer-Reviewed Journal Details
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O'Sullivan, SS, Neligan, A, Mullins, GM, Daly, S, McNamara, B, Galvin, RJ, Sweeney, BJ;
Journal of Clinical Neuroscience
Aetiology and Prognosis of Encephalopathic Patterns On Electroencephalogram In A General Hospital
Optional Fields
The purpose of this study was to investigate the frequency and clinical outcome of patients with encephalopathic electroencephalograms (EEGs) in a neurophysiology department based in a general hospital. We performed a retrospective review of all EEGs obtained during an 18-month period in a large tertiary referral hospital. The referral reasons for EEG, the diagnoses reached, and patient outcomes were reviewed according to EEG severity. One hundred and twenty-three patients with encephalopathic EEGs were reviewed. The most common referral reason found was for an assessment of a possible first-onset seizure. The most common diagnosis found was one of dementia or learning disability. Of patients who were followed-up for a median of 19 months, 20.7% had died. The mortality rate generally increased according to the severity of the encephalopathy on EEG. However, 21.4% of those patients with excessive theta activity only on EEG had died. This study highlights an increased mortality even in the apparently 'milder' degrees of EEG abnormalities. (C) 2007 Elsevier Ltd. All rights reserved..
DOI 10.1016/j.jocn.2007.04.004
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