Peer-Reviewed Journal Details
Mandatory Fields
O'Keeffe, S, Harrington, F, Maguire, AR;
2007
July
Synlett
Enantioselective Intramolecular Buchner Reaction of alpha-Diazoketones
Validated
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Optional Fields
-1
15
2367
2370

Enantioselectivities of up to 95% ee have been achieved in the intrarnolecular Buchner reaction catalysed by copper is oxazoline) complexes, the highest asymmetric inductions reported to date for this transformation. Significantly, use of a catalyst derived from a bis(oxazoline) ligand resulted in high enantioselectivities across several Substrates, indicating the possibility of developing a catalyst with general applicability..

DOI 10.1055/s-2007-986626
Grant Details