Barrett, E, Hayes, M, O'Connor, P, Gardiner, G, Fitzgerald, GF, Stanton, C, Ross, RP, Hill, C;

2007

June

Applied and Environmental Microbiology

Salivaricin P, One of A Family of Two-Component Antilisterial Bacteriocins Produced By Intestinal Isolates of Lactobacillus Salivarius

Validated

()

73

11

3719

3723

Lactobacfflus salivarius DPC6005, a porcine intestinal isolate, produces a two-component bacteriocin, salivaricin P, with homology to ABP-118 produced by a human probiotic L. salivarius strain. Indeed, molecular characterization revealed that while the peptides Sln1 and AIBP-118 alpha are identical, their companion peptides (Sln2 and ABP-118 beta, respectively) differ by two amino acids. This observation suggests that two-component bacteriocins may be a common feature of intestinal L. salivarius strains..