Peer-Reviewed Journal Details
Mandatory Fields
Shorten, G. D.,Gibbs, N. M.;
1993
Research In Veterinary Science
DOSE-RESPONSE RELATIONSHIP OF ATRACURIUM BESYLATE IN THE HALOTHANE-ANESTHETIZED PIG
Validated
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Optional Fields
55
33
392
393392
The dose response relationship for the intermediate-acting non-depolarising muscle relaxant, atracurium besylate in the pig was determined using evoked electromyography. An incremental dose technique was used in seven Large White/Landrace crossbred pigs anaesthetised with nitrous oxide and halothane. ED50 and ED95 were 510 +/- 87 mug kg-1 and 1150 +/- 270 mug kg-1, respectively. Although these values may represent an overestimate, they provide a reasonable guideline for the use of atracurium by veterinary anaesthetists.The dose response relationship for the intermediate-acting non-depolarising muscle relaxant, atracurium besylate in the pig was determined using evoked electromyography. An incremental dose technique was used in seven Large White/Landrace crossbred pigs anaesthetised with nitrous oxide and halothane. ED50 and ED95 were 510 +/- 87 mug kg-1 and 1150 +/- 270 mug kg-1, respectively. Although these values may represent an overestimate, they provide a reasonable guideline for the use of atracurium by veterinary anaesthetists.
0034-52880034-5288
://WOS:A1993MG83900025://WOS:A1993MG83900025
Grant Details